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Megazyme® β-Glucuronidase (Escherichia coli)

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High purity recombinant β-Glucuronidase (Escherichia coli) for use in research, biochemical enzyme assays and in vitro diagnostic analysis.
 
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Specifications
Brand Megazyme®
EC Number 3.2.1.31
Enzyme β-Glucuronidase
Storage Conditions Storage Temperature: 2-8°C Stability: > 1 year under recommended storage conditions
Formulation In solution (Tris.HCl/NaCl/EDTA)
Physical Form Solution
CAS Number 9001-45-0
CAZy Family GH2
Concentration ~ 250
Synonyms β-D-glucuronoside glucuronosohydrolase; GUS
Source Escherichia coli
Molecular Weight 82600
Expression Recombinant from Escherichia coli
Specificity Hydrolysis of non-reducing terminal β-D-glucuronic acid residues from glycoproteins and oligosaccharides of glycoconjugates.
Specific Activity ~ 15,000 U/mg (37°C, pH 6.8 on phenolphthalein-β-D-glucuronide); ~ 50 U/mg (37°C, pH 7.5 on pNP-β-D-glucuronide)
Unit Definition 30000 U/mg protein: One Unit of β-D-glucuronosidase activity is defined as the amount of enzyme required to release one µg of phenolphthalein per hour from phenolphthalein-β-D-glucuronide (0.5 mM) in sodium phosphate buffer (100 mM) at pH 6.8 and 37°C. 110 U/mg protein: One Unit of β-D-glucuronosidase activity is defined as the amount of enzyme required to release one µmole of p-nitrophenol per minute from pNP-β-D-glucuronide (1 mM) in Tris.HCl buffer (100 mM) pH 7.5 and 37°C., monitored at 410 nm.
Temperature Optima (°C) 37
pH Optima 6.8
Package Dimensions 0.70 in x 0.70 in x 1.60 in
Package Weight 0.03 lb
     

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